AUTOANTIBODIES IN SERUM OF SYSTEMIC SCLERODERMA PATIENTS: PEPTIDE-BASED EPITOPE MAPPING INDICATES INCREASED BINDING TO CYTOPLASMIC DOMAINS OF CXCR3

Autoantibodies in Serum of Systemic Scleroderma Patients: Peptide-Based Epitope Mapping Indicates Increased Binding to Cytoplasmic Domains of CXCR3

Systemic sclerosis (SSc) is a severe chronic autoimmune disease with high morbidity and mortality.Sera of patients with SSc contain a large variety of autoantibody (aab) reactivities.Among these are functionally active aab that bind to G protein-coupled receptors (GPCR) such as C-X-C motif chemokine receptor 3 (CXCR3) and 4 (CXCR4).Aab binding to t

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Strength and Damping Properties of Cementitious Composites Incorporating Original and Alkali Treated Flax Fibers

This experimental investigation focused on the mechanical and damping properties of raw and alkali treated flax fibers reinforced cementitious composites.The objective of this study was to research the influence of flax fiber for the damping properties of cementitious composites.The mechanical strengths were obtained using compressive and flexural

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Using an Internal State Variable Model Framework to Investigate the Influence of Microstructure and Mechanical Properties on Ballistic Performance of Steel Alloys

An internal state variable (ISV)-based constitutive model has been used within a Lagrangian finite element analysis (FEA) framework to simulate ballistic impact of monolithic rolled homogenous armor (RHA) steel plates by RHA steel spheres and cylinders.The ISV model predictions demonstrate good agreement with experimental impact data for spherical

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"A dream come true": Perspectives on long-acting injectable antiretroviral therapy among female sex workers living with HIV from the Dominican Republic and Tanzania.

BackgroundLong-acting injectable antiretroviral therapy (LA ART) was found to be non-inferior to daily oral ART in Phase 3 clinical trials.LA ART Cruiser may offer an important alternative for people living with HIV with challenges adhering to daily oral ART or preferences for non-pill-based regimens.MethodsUsing a mixed methods approach integratin

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